RNAi Screening Libraries
INTACT GENOMICS INC sgRNA Synthesis Kit for Cas12a Nuclease 10 Reactions (20 µl RXN Volume)
IG sgRNA Synthesis Kits are a perfect choice for a variety of sgRNA synthesis needs. Below is a sampling of some of the key benefits. IG sgRNA Synthesis Kit includes everything but your targeting oligo (all buffers, enzymes, scaffolds) User simply needs to provide the oligo for your target—Must be 55 base pairs and generated using the template design in this manual. Rapid Workflow (Less than 1 hour) Scalable Yield (just 1 reaction for all the sgRNA you need) Customer support – our team is available to aid with your success.IG sgRNA Synthesis Kits contains the items below. Store all components at -20°C. IG sgRNA Enzyme Mix (10X) IG sgRNA Reaction Mix, S. pyogenes (4X) DNase I (RNase-free, 2 Units/uL) IG sgRNA Control Oligo, S. pyogenes (1 uM) Dithiothreitol (DTT, 0.2 M) NTPs mix (25 mM)
INTACT GENOMICS INC sgRNA Synthesis Kit for Cas9 Nuclease 10 Reactions (100 µl RXN Volume)
IG sgRNA Synthesis Kits are a perfect choice for a variety of sgRNA synthesis needs. Below is a sampling of some of the key benefits. IG sgRNA Synthesis Kit includes everything but your targeting oligo (all buffers, enzymes, scaffolds) User simply needs to provide the oligo for your target—Must be 55 base pairs and generated using the template design in this manual. Rapid Workflow (Less than 1 hour) Scalable Yield (just 1 reaction for all the sgRNA you need) Customer support – our team is available to aid with your success.IG sgRNA Synthesis Kits contains the items below. Store all components at -20°C. IG sgRNA Enzyme Mix (10X) IG sgRNA Reaction Mix, S. pyogenes (4X) DNase I (RNase-free, 2 Units/uL) IG sgRNA Control Oligo, S. pyogenes (1 uM) Dithiothreitol (DTT, 0.2 M) NTPs mix (25 mM)
Cayman Chemical Humn TropomysIn Receptr KIn 96
An internal standard for the quantification of malathion by GC- or LC-MS
Cayman Chemical Humn LIvR Receptr Homolog 96
Inhibitor of Cdk1/cyclin B and Cdk/p25 (IC50s 600 and 400 nM respectively)
Cayman Chemical Humn LIvR Receptr Homolog 384
A multiple kinase inhibitor blocking Met Tie2 VEGF2 TrkA TrkB and TrkC with IC50 values of 2 7 8 0 9 2 0 85 4 6 and 0 83 nM respectively orally bioavailable and penetrates the blood brain barrier suppressing the growth of subcutaneous and intracerebroventricular xenograft tumors in mice
Cayman Chemical sn-glycero-3-PhosphocholIn 25g
A fluorescent probe that crosses the blood-brain barrier binds with high affinity to AB plaques (Ki 10 nM) ex/em spectra 475/625 nm respectively far-red emission occurs upon binding to AB
Cayman Chemical Mouse LIvR X Receptr Alpha 96
A PEGylated form of cholesterol has been used in the synthesis of liposomes for targeted drug delivery
Cayman Chemical TrnsfRrIn Receptr ProteIn 50uL
A phenylethanoid glycoside selectively inhibits aldose reductase over maltase and sucrase (IC50s 0.071 300 and 277 UM respectively for the rat enzymes) scavenges superoxide radicals in a cell-free assay and inhibits AAPH-induced hemolysis in isolated rat red blood cells decreases glutamate-induced cytotoxicity in primary rat cortical neurons at 0.1 1 and 10 UM protects primary mouse hepatocytes against D-galactosamine-induced cytotoxicity (IC50 4.8 Ug/ml) prevents decreases in bone strength in ovariectomized mice from 10-40 mg/kg
Cayman Chemical OrexIn 2 Receptr ReporTR1ea
A linker molecule has been used to conjUGate SN-38 to phlorizin or phloretin to increase the selectivity of SN-38 for cancer cells
Cayman Chemical MelnocortIn4 Receptr Rever 1ea
An MC4R antagonist selectively inhibits [Nle4D-Phe7]-a-MSH binding to recombinant human MC4R over MC1R and MC3R (IC50s 11.63 >10000 and 1115 nM respectively) inhibits a-MSH-induced cAMP production in COS-1 cells expressing human MC4R from 0.1-100 UM reduces stress-induced decreases in the time spent in the light area of the light/dark exploration test in mice reverses restraint stress-induced decreases in food intake in rats
Cayman Chemical 1 2 3TrInonadecnoyl Glycero 1g
An internal standard for the quantification of vigabatrin by GC- or LC-MS
Cayman Chemical MelatonIn Receptr TYP 1Ah 10ug
A selective estrogen receptor modulator binds to ERa and ERB (Kis 380 and 410 nM respectively) increases vaginal weight and vaginal epithelial height (ED50s 0.48 and 0.39 mg/kg per day respectively) in an ovariectomized rat model of menopause increases progesterone receptor protein expression in vaginal epithelium and stroma and inhibits 17b-estradiol-induced estrogen response element-mediated transactivation in a reporter assay using MCF-7 cells
Cayman Chemical MInralocortIcoId Receptr BI 96
An internal standard for the quantification of myclobutanil by GC- or LC-MS